| CASE |
| Nasopharyngeal non-keratinizing carcinoma, undifferentiated. |
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| HISTORY |
| A 72 year old woman with nose bleed. |
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| MICROSCOPIC DETAILS |
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| Fig. 1 |
Fig. 2 |
Fig. 3 |
Fig. 4 |
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| Fig. 1- Low power magnification of the biopsy from the nasopharynx. |
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| Fig. 2- High power view of highly atypical cells growing in a syncytial pattern. |
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| Fig. 3- Cytokeratin stain highlighting the atypical cells. |
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| Fig. 4- Immunohistochemical stain with LCA (CD45). |
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| DIAGNOSIS |
| Nasopharyngeal non-keratinizing carcinoma, undifferentiated. |
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| DISCUSSION |
| Sections reveal large tumor cells growing in a syncytial pattern with indistinct tumor borders, round to oval nuclei and large, central nucleoli. The cytoplasm is eosinophilic. Tumor cells are separated by stroma filled with lymphocytes. This morphology is consistent with nasopharyngeal carcinoma. |
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| REFERENCES |
| Upon request |
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